降钙素基因相关肽与运动性疲劳的潜在关系(5)
来源:学术堂 作者:原来是喵
发布于:2016-10-28 共11422字
4结论
CGRP干预后,大鼠运动至力竭的时间明显下降,骨骼肌的细胞核明显增多、增大,MDA的含量上升,SOD、GSH-PX和CAT的活性下降,提示,CGRP可能介导了运动性疲劳的产生。
参考文献:
[1]戚正本。多核细胞的形成机理及其运动医学意义[J].体育成人教育学刊,2007,23(6):49-51.
[2]BAYRAKTAR N,KILIC S,BAYRAKTAR M R,et al.Lipidperoxidation and antioxidant enzyme activities in cancerous blad-der tissue and their relation with bacterial infection:A controlledclinical study[J].J Clin Lab Anal,2010,24(1):25-30.
[3]BEDFORD T G,TIPTON C M,WILSON N C,et al.Maximumoxygen consumption of rats and its changes with various experi-mental procedures[J].J Appl Physiol,1979,47(6):1278-1283.
[4]BELL D,MCDERMOTT B J.Calcitonin gene-related peptide inthe cardio-vascular system:Characterization of receptor popula-tions and their(patho)physiological significance[J].PharmacolRev,1996,48(2):253-288.
[5]BLESCH A,TUSZYNSKI M H.GDNF gene deliveryto injuredadult CNS motor neurons promotes axonal growth,expression ofthe trophic neuropeptide CGRP,and cellular protection[J].JCompNeurol,2001,436(4):399-410.
[6]CALDER?J,TARABAL O,CASANOVAS A,et al.Excitotoxicmotoneuron disease in chick embryo evolves with autophagicneurodegeneration and deregulation of neuromuscular innerva-tion[J].J Neurosci Res,2007,85(12):2726-2740.
[7]CARMICHAEL M D,DAVIS J M,MURPHY E A,et al.Roleof brain macrophages on IL-1beta and fatigue followingeccentricexercise-induced muscle damage[J].Brain Behav Immun,2010,24(4):564-568.
[8]CHI A,LI H,KANG C,et al.Anti-fatigue activityof a novelpolysaccharide conjugates from Ziyanggreen tea[J].Int J BiolMacromol,2015,80:566-572.
[9]FAN W,WU X,PAN Y,et al.1-(1,3-Benzodioxol-5-yl-carbo-nyl)piperidine,a modulator ofα-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor,ameliorates exercise-inducedfatigue in mice[J].Biol Pharm Bull,2014,37(1):13-17.
[10]FERNANDEZ H L,ROSS G S,NADELHAFT I.Neurogeniccalcitonin gene-related peptide:A neurotrophic factor in themaintenance of acetylcholinesterase molecular forms in adultskeletal muscles[J].Brain Res,1999,844(1-2):83-97.
[11]FLEMING N W,LEWIS B K,WHITE D A,et al.Acute effectsof calcitonin gene-related peptide on the mechanical and electri-cal responses of the rat hemidiaphragm[J].J Pharmacol ExpT-her,1993,265(3):1199-1204.
[12]GARDINER S M,COMPTON A M,KEMP P A,et al.Haemo-dynamic effects of human a-calcitonin gene-related peptide fol-lowingadministration of endothelin-1 or N-nitro-Largininemethyl ester in conscious rats[J].Br J Pharmacol,1991,103(1):1256-1262.
[13]HOMONKO D A,THERIAULT E.Calcitonin gene-related pe-ptide is increased in hindlimb motoneurons after exercise[J].Int J Sports Med,1997,18:1-7.
[14]KIM K C,KANG K A,ZHANG R,et al.Risk reduction of eth-yl acetate fraction of Empetrum nigrum var.Japonicum via an-tioxidant properties against hydrogen peroxide-induced celldamage[J].J Toxicol Environ Health A,2009,72(21-22):1499-1508.
[15]KLOOT W V D,BENJAMIN W B,BALEZINA O P.Calcitoningene-related peptide acts presynapticallyto increase quantalsize and output at frogneuromuscular junctions[J].J Physiol,1998,507(Pt3):689-695.
[16]LIANG Y,FANG J Q,WANG C X,et al.Effects of transcuta-neous electric acupoint stimulation on plasma SOD and MDA inrats with sports fatigue[J].Acupuncture Res,2008,33(2):120-123.
[17]LU J T,SON Y J,LEE J,et al.Mice lackingalpha-calcitoningene-related peptide exhibit normal cardiovascular regulationand neuromuscular development[J].Mol Cell Neurosci,1999,14(2):99-120.
[18]UCZAJ W,ZAPORA E,SZCZEPA?SKI M,et al.Polyphe-nols action against oxidative stress formation in endothelialcells[J].Acta Pol Pharm,2009,66(6):617-624.
[19]MAGAL M,DUMKE C L,URBIZTONDO Z G,et al.Rela-tionshipbetween serum creatine kinase activityfollowingexer-cise-induced muscle damage and muscle fibre composition[J].JSports Sci,2010,13:1-10.
[20]MARQUES M J,MINATEL E,GUIMARV?ES A O,et al.Distribution of calcitonin gene-related peptide at the neuromus-cular junction of mdx mice[J].Anat Rec A Discov Mol CellEvol Biol,2004,279(2):798-803.
[21]MATSUMOTO N,UCHIDA S,WANG X B,et al.Effect ofdenervation of the phrenic nerve on the action of calcitoningene-related peptide in rat diaphragm[J].Life Sci,1990,47(6):547-555.
[22]NAVES L A,KLOOT W V D.Repetitive nerve stimulation de-creases the acetylcholine content of quanta at the frogneuro-muscular junction[J].J Physiol,2001,532(Pt3):637-647.
[23]NAZIROGLU M,CIHANGIR UGUZ A,KO?AK A,et al.Ac-etaminophen at different doses protects brain microsomal Ca2+-ATPase and the antioxidant redox system in rats[J].J MembrBiol,2009,231(2-3):57-64.
[24]RINGER C,WEIHE E,SCH?TZ B.Pre-symptomatic altera-tions in subcellular betaCGRP distribution in motor neuronsprecede astrogliosis in ALS mice[J].Neurobiol Dis,2009,35(2):286-295.
[25]ROSA E,CHA J,BAIN J R,et al.Calcitonin gene-related pep-tide regulation of glial cell-line derived neurotrophic factor indifferentiated rat myotubes[J].J Neurosci Res,2015,93(3):514-520.
[26]SHE F,SUN W,MAO J M,et al.Calcitonin gene-related pep-tide gene therapysuppresses reactive osygen species in the pan-creas and prevents mice from autoimmune diabetes[J].ActaPhysiologica Sinica,2003,55(6):625-632.
[27]SIECK G C,PRAKASH Y S.Fatigue at the neuromuscularjunction.Branch point vs.presynaptic vs.postsynaptic mecha-nisms[J].Adv ExpMed Biol,1995,384:83-100.
[28]THOMSON R L,ROGERS D K,HOWE P R,et al.Effect of acuteexercise-induced fatigue on maximal rate of heart rate increase dur-ingsubmaximal cycling[J].Res Sports Med,2015,20:1-15.
[29]TORGAN C E,KRAUS W E.Regulation of type II adenylylcyclase mRNA in rabbit skeletal muscle bychronic motor nervepacing[J].Am J Physiol,1996,271(2Pt 1):E253-260.
[30]UCHIDA S,YAMAMOTO H,IIO S,et al.Release of calcito-nin gene-related peptide-like immunoreactive substance fromneuromuscular junction bynerve excitation and its action onstriated muscle[J].J.Neurochem,1990,54(3):1000-1003.
[31]URBANO F J,LINO N G,GONZ?LEZ-INCHAUSPE C M,etal.Acid-sensingion channels 1a(ASIC1a)inhibit neuromuscu-lar transmission in female mice[J].Am J Physiol Cell Physiol,2014,306(4):C396-406.
[32]WEBER T,DUCOS M,MULDER E,et al.The relationshipbe-tween exercise-induced muscle fatigue,arterial blood flow andmuscle perfusion after 56days local muscle unloading[J].ClinPhysiol Funct Imaging,2014,34(3):218-29.
[33]YANG Q,JIN W,LV X,et al.Effects of macamides on endur-ance capacityand anti-fatigue propertyin prolonged swimmingmice[J].Pharm Biol,2015,9:1-8.
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