机械应力对骨骼不同细胞的作用分析(3)

　　6参考文献
　　1 Belavy DL,Baecker N,Armbrecht G,et al. Serum sclerostin and DKK1 inrelation to exercise against bone loss in experimental bed rest〔J〕。 J BoneMiner Metab,2015;71:237-43.
　　2 Ohshim AH,Matsumoto T. Space flight / bedrest immobilization and bone.Bone metabolism in space flight and long-duration bed rest〔J〕。 Clin Cal-cium,2012;22（12） :1803-12.
　　3 Prior JC,Langsetmo L,Lentle B C,et al. Ten-year incident osteoporosis-related fractures in the population-based Canadian Multicentre Osteoporo-sis Study -comparing site and age-specific risks in women and men〔J〕。Bone,2015;71:237-43.
　　4 Wang QS,Zhang XC,Li RX,et al. A comparative study of mechanicalstrain,icariin and combination stimulations on improving osteoinductivepotential via NF-kappa B activation in osteoblast-like cells 〔J〕。 BiomedEng Online,2015;14:46.
　　5 Nuttall ME,Gimble JM. Is there a therapeutic opportunity to either pre-vent or treat osteopenic disorders by inhibiting marrow adipogenesis〔J〕Bone,2000;27（2） :177-84.
　　6 Case N,Thomas J,Xie Z,et al. Mechanical input restrains PPARgamma2expression and action to preserve mesenchymal stem cell multipotentiality〔J〕。 Bone,2013;52（1） :454-64.
　　7 Wiesmann A,Buhring HJ,Mentrup C,et al. Decreased CD90 expressionin human mesenchymal stem cells by applying mechanical stimulation〔J〕。 Head Face Med,2006;2:8.
　　8 Sumanasinghe RD,Bernacki SH,Loboae G. Osteogenic differentiation ofhuman mesenchymal stem cells in collagen matrices:effect of uniaxialcyclic tensile strain on bone morphogenetic protein（BMP-2）mRNA ex-pression〔J〕。 Tissue Eng,2006;12（12） :3459-65.
　　9 Simmons CA,Matlis S,Thornton AJ,et al. Cyclic strain enhances matrixmineralization by adult human mesenchymal stem cells via the extracellu-lar signal-regulated kinase（ERK1 /2）signaling pathway〔J〕。 J Biomech,2003;36（8） :1087-96.
　　10 Meyers VE,Zayzafoon M,Douglas JT,et al. Rho A and cytoskeletal dis-ruption mediate reduced osteoblastogenesis and enhanced adipogenesisof human mesenchymal stem cells in modeled microgravity〔J〕。 J BoneMineral Res,2005;20（10） :1858-66.
　　11 Maredziak M,Smieszek A,Chrzastek K,et al. Physical activity increasesthe total number of bone-marrow-derived mesenchymal stem cells,en-hances their osteogenic potential,and inhibits their adipogenic properties〔J〕。 Stem Cells Int,2015;2015:379093.
　　12 Menuki K,Mori T,Sakai A,et al. Climbing exercise enhances osteoblastdifferentiation and inhibits adipogenic differentiation with high expres-sion of PTH / PTHr P receptor in bone marrow cells〔J〕。 Bone,2008;43（3） :613-20.
　　13 Rubin J,Rubin C,Jacobs CR. Molecular pathways mediating mechanicalsignaling in bone〔J〕。 Gene,2006;367:1-16.
　　14 Huiskes R,Ruimerman R,van Lenthe GH,et al. Effects of mechanicalforces on maintenance and adaptation of form in trabecular bone 〔J〕。Nature,2000;405（6787） :704-6.
　　15 Wang QS,Zhang XC,Li RX,et al. A comparative study of mechanicalstrain,icariin and combination stimulations on improving osteoinductivepotential via NF-kappa B activation in osteoblast-like cells〔J〕。 BiomedEng Online,2015;14（1） :46.
　　16 Guo Y,Zhang CQ,Zeng QC,et al. Mechanical strain promotes osteoblastECM formation and improves its osteoinductive potential 〔J〕。 BiomedEng Online,2012;11:80.
　　17 Zhong Z,Zeng XL,Ni JH,et al. Comparison of the biological response ofosteoblasts after tension and compression 〔J〕。 Eur J Orthod,2013;35（1） :59-65.
　　18 Myers KA,Rattner JB,Shrive NG,et al. Osteoblast-like cells and fluidflow:cytoskeleton-dependent shear sensitivity〔J〕。 Biochem Biophy ResComm,2007;364（2） :214-9.
　　19 Du D,Furukawa KS,Ushida T. 3D culture of osteoblast-like cells by u-nidirectional or oscillatory flow for bone tissue engineering〔J〕。 Biotech-nol Bioeng,2009;102（6） :1670-8.
　　20 Lester ME,Urso ML,Evans RK,et al. Influence of exercise mode andosteogenic index on bone biomarker responses during short-term physicaltraining〔J〕。 Bone,2009;45（4） :768-76.
　　21 Kish K,Mezil Y,Ward WE,et al. Effects of plyometric exercise sessionon markers of bone turnover in boys and young men 〔J〕。 Eur J AppPhys,2015;115（10） :2115-24.
　　22 Burgers TA,Williams BO. Regulation of Wnt / beta-catenin signalingwithin and from osteocytes〔J〕。 Bone,2013;54（2） :244-9.
　　23 Tatsumi S,Ishii K,Amizuka N,et al. Targeted ablation of osteocytes in-duces osteoporosis with defective mechanotransduction〔J〕。 Cell Metab,2007;5（6） :464-75.
　　24 Schriefer JL,Warden SJ,Saxon LK,et al. Cellular accommodation andthe response of bone to mechanical loading〔J〕。 J Biom,2005;38（9） :1838-45.
　　25 Mann V,Huber C,Kogianni G,et al. The influence of mechanical stimu-lation on osteocyte apoptosis and bone viability in human trabecularbone〔J〕。 J Musculoskelet Neuron Interact,2006;6（4） :408-17.
　　26 Cui L,Li XT,Zhang D. Effect of fluid flow-induced shear stress on oste-oclast formation induced by osteocyte 〔J〕。 Acta Academ Med Sinicae,2012;34（3） :207-11.
　　27 Cherian PP,Cheng B,Gu S,et al. Effects of mechanical strain on thefunction of Gap junctions in osteocytes are mediated through the prosta-glandin EP2 receptor〔J〕。 J Biolog Chem,2003;278（44） :43146-56.
　　28 Iijima H,Aoyama T,Ito A,et al. Effects of short-term gentle treadmillwalking on subchondral bone in a rat model of instability-induced osteo-arthritis〔J〕。 Osteoarthritis Cartilage,2015;23（9） :1563-74.
　　29 Maurel DB,Boisseau N,Pallu S,et al. Regular exercise limits alcoholeffects on trabecular,cortical thickness and porosity,and osteocyte apop-tosis in the rat〔J〕。 Joint Bone Spine,2013;80（5） :492-8.
　　30 Swift JM,Swift SN,Nilsson MI,et al. Cancellous bone formation re-sponse to simulated resistance training during disuse is blunted by con-current alendronate treatment〔J〕。 J Bone Mineral Res,2011;26（9） :2140-50.
　　31 Fonseca H,Moreira-Goncalves D,Esteves JL,et al. Voluntary exercisehas long-term in vivo protective effects on osteocyte viability and bonestrength following ovariectomy 〔J 〕。 Calc Tissue Int,2011;88（6） :443-54.
　　32 Rubin J,Fan X,Biskobing DM,et al. Osteoclastogenesis is repressed bymechanical strain in an in vitro model 〔J〕。 J Orthopaed Res,1999;17（5） :639-45.
　　33 Rubin J,Murphy T,Nanes MS,et al. Mechanical strain inhibits expres-sion of osteoclast differentiation factor by murine stromal cells〔J〕。 AmeJ Physiol Cell Physiol,2000;278（6） :C1126-32.
　　34 Rubin J,Murphy TC,Zhu L,et al. Mechanical strain differentially regu-lates endothelial nitric-oxide synthase and receptor activator of nuclearkappa B ligand expression via ERK1 /2 MAPK〔J〕。 J Biol Chem,2003;278（36） :34018-25.
　　35元宇，郭健民，邹军。 OPG / RANKL / RANK信号通路在运动与骨免疫学中的研究进展〔J〕。中国骨质疏松杂志，2015;21（8） :1005-10.
　　36 Kaneuji T,Ariyoshi W,Okinaga T,et al. Mechanisms involved in regula-tion of osteoclastic differentiation by mechanical stress-loaded osteo-blasts〔J〕。 Biochem Biophy Res Comm,2011;408（1） :103-9.
　　37 Takayanagi H,Ogasawara K,Hida S,et al. T-cell-mediated regulation ofosteoclastogenesis by signalling cross-talk between RANKL and IFN-gamma〔J〕。 Nature,2000;408（6812） :600-5.
　　38 Hayashida C,Ito J,Nakayachi M,et al. Osteocytes produce interferon-beta as a negative regulator of osteoclastogenesis 〔J 〕。 J Biol Chem,2014;289（16） :11545-55.
　　39 Suzuki N,Yoshimura Y,Deyama Y,et al. Mechanical stress directlysuppresses osteoclast differentiation in RAW264. 7 cells〔J〕。 Int J MolMed,2008;21（3） :291-6.
　　40 Nagatomi J,Arulanandam BP,Metzger DW,et al. Effects of cyclic pres-sure on bone marrow cell cultures 〔J〕。 J Biomechan Eng,2002;124（3） :308-14.
　　41 Wu SH,Zhong ZM,Chen JT. Low-magnitude high-frequency vibrationinhibits RANKL-induced osteoclast differentiation of RAW264. 7 cells〔J〕。 Int J Med Sci,2012;9（9） :801-7.