8预防及疫苗研发进展。
8.1 预防控制 主要预防措施是防止被蚊虫叮咬,方法包括:喷洒防虫剂,穿长袖衣长裤,使用纱窗、蚊帐,消除蚊虫繁衍及聚集地等。孕妇尽量不去寨卡病毒流行区,对已经感染寨卡病毒的孕妇,建议定期产检,每3~4周监测胎儿生长发育情况。
8.2 疫苗研发 针对寨卡病毒目前无特效疫苗。2016 年 6 月,美国和巴西研究人员证实2种候选寨卡病毒疫苗在动物实验中能有效保护小鼠免受寨卡病毒感染[38].8 月,Abbink 等[39]的研究表明3种寨卡疫苗都能为猴子提供完全的保护。11 月,美国沃尔特里德陆军研究所启动了寨卡纯化灭活病毒疫苗的临床(Ⅰ期)研究[40].接下来数月中,还将启动四批不同的临床(Ⅰ期)实验,分别由不同的单位实施。有关寨卡病毒疫苗的效果将在2017 年得到验证。
9结论。
随着我国经济发展,与其他国家、地区间贸易及旅游业日益增多,输入性寨卡病毒感染者是需要严控监测的传染源,特别是在清明节期间,随着回乡祭祖人员增多,存在输入病例的可能;随着春季的到来,气温逐日升高,蚊虫也会越来越多,尤其是在有寨卡病毒蚊媒的地区,更应该警惕寨卡病毒的本地传播。总的来说,就是外防输入,内防扩散。同时,各地政府有关机构应向公众提供寨卡病毒病的健康知识宣传,提高疾病检测与反应能力,全面加强虫媒疾病预防控制。寨卡病毒及其所引发的神经系统疾病仍是一个显着持续的公共卫生问题,我国应不断向前推进寨卡病毒的研究、寨卡病毒疫苗的研制及其他一些项目。
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